Lifestyle

Promising pre-clinical cancer therapy harnesses a newly discovered cell death pathway

St. Jude Children’s Research Hospital scientists have identified a new strategy that takes advantage of an unexpected regulator of inflammatory cell death to shrink tumors in mice. The study appeared today in Cell Reports. One key hallmark of cancer is the ability of tumor cells to resist cell death. In her research, Thirumala-Devi Kanneganti, Ph.D., […]

Lifestyle

Genetic testing of the siblings of newborns with cancer genes could reduce rare pediatric cancer deaths by half

Genetic testing of the siblings of newborns found to have mutations in any one of 11 genes most commonly associated with childhood-onset cancers could reduce deaths from these rare cancers by about 50%, suggests a study funded by the National Institutes of Health. Moreover, such routine testing could save nearly $17,000 per year for each […]

Lifestyle

Epilepsy research reveals previously unknown trigger for seizures

Researchers at the University of Virginia School of Medicine have uncovered how problems in cortical microcircuits in the brain can trigger epileptic seizures. The researchers say that targeting the problem could lead to new treatments for a devastating form of the disease. UVA epilepsy researchers Eric R. Wengert and Manoj K. Patel and their team […]

Lifestyle

Researchers find novel means of flagging inpatient pharmacy orders for intervention

Medication order errors are a significant, and preventable, public health problem. The widespread deployment of electronic health records and computerized order entry systems has largely reduced medication order errors and inefficiencies in the inpatient setting. Emerging research suggests, however, that they have also introduced new sources of error related to the interaction between the provider […]

Lifestyle

Novel sugar detector system in the human mouth has implications for designing tastier, healthier beverages and foods

Most everyone understands that a major role of our sense of taste is to inform us when sugar is present in foods and beverages by eliciting sweetness on our tongues. A study led by the Monell Chemical Senses Center, published this month in PLOS ONE, identifies a new human sensory ability to detect sugars in […]

Lifestyle

Corporate influence linked to slow implementation of public health policies globally

Implementation of WHO’s recommended public health policies on alcohol, unhealthy foods and tobacco has been slow globally, according to a study led by researchers at Karolinska Institutet and the London School of Hygiene & Tropical Medicine, published in the journal The Lancet Global Health. The study found particularly low implementation in poor, less democratic countries […]

Lifestyle

Targeted prostate cancer screening could benefit men with inherited cancer syndrome

Men who inherit an increased risk of cancer through “Lynch syndrome” could benefit from regular PSA testing from age 40 to detect early signs of prostate cancer, researchers believe. Lynch syndrome raises the risk of several cancer types including—most famously—bowel cancer, and affects 175,000 people in the UK, although only 5 percent of people with […]